And finally, clonidine boosts neuraxial opioids and, in combination with fentanyl, interacts in an additive fashion, that may lessen the dose of every ingredient by 60% for postoperative analgesia. Clonidine treats large blood pressure by stimulating α2 receptors inside the brainstem, which decreases peripheral vascular resistance, decreasing blood pressure. https://billyd023auq0.daneblogger.com/profile